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Gene Segment Reassortment Between American and Asian Lineages of Avian Influenza Virus from Waterfowl in the Beringia Area
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2008 (English)In: Vector Borne and Zoonotic Diseases, ISSN 1530-3667, E-ISSN 1557-7759, Vol. 8, no 6, p. 783-790Article in journal (Refereed) Published
Abstract [en]

Since prehistoric times, the Bering Strait area (Beringia) has served as all avenue of dispersal between the Old and the New Worlds. On a field expedition to this area, we collected fecal samples from dabbling ducks, geese, shorebirds, and gulls on the Chukchi Peninsula, Siberia, and Pt. Barrow, Alaska, and characterized the sub-types of avian influenza virus present in them. Four of 202 samples (2%) from Alaska were positive for influenza A virus RNA in two independent polymerase chain reaction (PCR)-based screening assays, while all shorebird samples from the Chukchi Peninsula were negative. Subtypes H3N8 and H6N1 were recorded once, while subtype H8N4 was found in two samples. Full-length sequences were obtained from the three unique isolates, and phylogenetic analysis with representative sequences for the Eurasian and North American lineages of influenza A virus showed that one HA gene Clustered with the Eurasian rather than the North American lineage. However, the closest relative to this sequence was a North American isolate from Delaware described in 2002, indicating that a H6 spillover from Asia has established itself in North America.

Place, publisher, year, edition, pages
2008. Vol. 8, no 6, p. 783-790
Keywords [en]
Avian influenza; Eurasian lineage; American lineage
National Category
Natural Sciences
Research subject
SWEDARCTIC 2005, Beringia 2005
Identifiers
URN: urn:nbn:se:polar:diva-3122DOI: 10.1089/vbz.2007.0274OAI: oai:DiVA.org:polar-3122DiVA, id: diva2:1049846
Available from: 2016-11-25 Created: 2016-11-21 Last updated: 2017-11-29

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